01
RANDOMIZED CONTROLLED TRIAL⚠ SMALL SAMPLE SIZE (26 PARTICIPANTS ACROSS TWO TREATMENT GROUPS).
Injected vitamin C significantly reduced gum pigmentation in a controlled trial.
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SKINCARE
• BACKED
Vitamin C for Pigmentation
RESEARCH
- Reduces dark spots
- Blocks melanin production
- Works best injected
- Takes weeks to months
COMMUNITY
- Limited discussion found
⚠
SAFETYVitamin C can irritate sensitive skin; start with lower concentrations and check with a dermatologist if pregnant or using other depigmenting treatments.
WHAT THE RESEARCH SAYS
ALL 15 ON PUBMED ↗BASED ON 15 PUBMED STUDIES
02
RANDOMIZED CONTROLLED TRIAL⚠ SMALL SAMPLE (20 PARTICIPANTS); DIFFERENT TREATMENT DURATIONS BETWEEN GROUPS (3 WEEKS VS. 3 MONTHS).
Vitamin C mesotherapy reduced gum pigmentation more effectively than topical gel application.
03
RANDOMIZED CONTROLLED TRIAL⚠ COMBINATION TREATMENT (NOT VITAMIN C ALONE); NO DIRECT COMPARISON TO VITAMIN C MONOTHERAPY.
Vitamin C combined with microneedling reduced facial dark spots under the eyes in a trial.
04
META-ANALYSIS⚠ HIGH HETEROGENEITY BETWEEN STUDIES; MOST EVIDENCE FOCUSES ON GINGIVAL (GUM) HYPERPIGMENTATION, NOT FACIAL SKIN PIGMENTATION.
A meta-analysis of 11 trials found vitamin C mesotherapy significantly reduced visible pigmentation.
WHAT PEOPLE SAY
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COMMENTS
Add context that might help others — skin type, conditions like PCOS, what you'd tried before. The more specific, the more useful.
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